Research Initiative Presented at ESVS 2025 Istanbul

Expert-Level Interpretation of Clinical
Practice Guidelines

An independent pilot demonstrating how GraphRAG AI delivers guideline-locked, hallucination-free answers.

Our Mission

Bridging the gap between complex clinical guidelines and actionable, evidence-based decisions at the point of care.

Knowledge Synthesis

Transform dense 200+ page clinical guidelines into instantly queryable intelligence.

Clinical Accuracy

Every recommendation traced to specific guideline sections with evidence class and level.

Zero Hallucination

If the answer isn't in the guidelines, the AI explicitly refuses to guess.

The Crucible: Benchmarking Against the Masters

We tested the engine against 41 clinical vignettes authored by the ESC/ESVS Writing Committee.

90.5%

AI Performance Score

vs 77.8% for Committee Exemplars

Non-Inferior

Across All 12 Metrics

p < 0.001 Safety Margin

Zero

Hallucinations

100% Citation Lock-in

Why Standard AI Fails Medicine

Understanding the critical difference between general-purpose LLMs and our GraphRAG approach.

01

The Problem: Hallucination

Generic LLMs invent facts when they don't know the answer. This is a non-starter for vascular surgery where patient safety depends on accurate information.

02

The Solution: Guideline Lock-in

Our GraphRAG engine creates a mathematical boundary. If the answer isn't in the PDF, the AI explicitly refuses to guess, ensuring absolute fidelity to source material.

03

Traceable Evidence

Every response includes a "Trace Drawer" linking to the specific paragraph and evidence level (Class I, Level B), enabling verification at the source.

Scientific Leadership

A multidisciplinary team of vascular surgeons and researchers.

Vangelis Alexiou, MD, PhD

Vascular Surgeon & Developer

University Hospital of Ioannina, Greece

Areti Vassiliou, MD, MSc

Vascular Surgeon

Attikon University Hospital, Athens

Prof. Bauer E. Sumpio, MD, PhD

Professor of Surgery

Yale University School of Medicine, USA

Prof. George Geroulakos, MD, PhD

Professor of Vascular Surgery

National and Kapodistrian University of Athens

Prof. Stavros K. Kakkos, MD, PhD

Professor of Vascular Surgery

University Hospital of Patras, Greece

Join the Pilot Program

Request access to the beta. Approved clinicians will be redirected to the secure chat interface.